B Cell Aplasia and Hypogammaglobulinemia after Carbamazepine Treatment
نویسندگان
چکیده
منابع مشابه
Carbamazepine-induced hypogammaglobulinemia
Carbamazepine is used to control seizures. Its common side effects are sleep disorders, anorexia, nausea, vomiting, polydipsia, irritability, ataxia, and diplopia. Involvement of the immune system is rare, and few cases of decreased immunoglobulin levels have been reported. We describe a patient with low immunoglobulin levels due to carbamazepine use who presented with recurrent urinary tract i...
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A 2-year-old boy developed pure red cell aplasia (PRCA) during carbamazepine (CBZ) therapy. There was no history of prolonged or profuse bleeding after cuts or injury, and no bleeding from any sites of the body, petechiae, ecchymosis, or bruising. His family history of hematological disorders was negative. The child had been receiving CBZ therapy at a daily dose of 10 mg kg–1 for the last 6 mon...
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A 72-yr-old male with Tr-cell chronic lymphocytic leukemia (Tr-CLL) exhibited pure red cell aplasia (PRCA) and hypogammaglobulinemia. During a remission of Tr-CLL, and while receiving cyclophosphamide therapy, he recovered from PRCA and hypogammaglobulinemia. To investigate the pathogenesis of PRCA and hypogammaglobulinemia, we used coculture techniques to study the effect of the malignant Tr c...
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A 38-y-old woman with Down syndrome was admitted to hospital for investigation of a 6-mo history of anorexia and weight loss of 40 lbs. Six months prior to admission, her weight was 175 lbs, and her body mass index was 36. On admission, her complete blood count was normal, but over a 2-wk period she developed acute pancytopenia (Figure 1). During this acute episode, her lowest hematological par...
متن کاملCarbamazepine-induced interstitial pneumonitis associated with pan-hypogammaglobulinemia
Carbamazepine remains a first-line drug for treatment of epilepsy in children. A wide variety of side effects have been attributed to its use, including a mild involvement of the immune system, usually a transient decline in IgA. Pulmonary complications, including interstitial pneumonitis, were mainly described in adults, and are considered rare side effects. In this report we describe the firs...
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ژورنال
عنوان ژورنال: Internal Medicine
سال: 2010
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.49.3087